| 초록 |
Clostridium acetobutylicum is an attention-grabbing bacterium in that it produces several solvents, especially butan-1-ol. We reconstructed a genome-scale metabolic network of C. acetobutylicum ATCC 824 which comprises 502 reactions and 479 metabolites. Then, we carried out flux balance analysis using both linear and non-linear approach which is a modification of previous studies. Here, we present metabolic features and feasibilities of C. acetobutylicum, and hypothetical annotations derived during the reconstruction of the network. [This work was supported by the Korean Systems Biology Research Project (M1030902000003B500200000) of the Ministry of Education, Science and Technology. Further supports by the LG Chem Chair Professorship, Microsoft, and IBM SUR program are appreciated.] |
