| 초록 |
Cancer cells release abnormal gas composition compared with that of normal cells. Therefore, cancer can be diagnosed by breath testing for a unique composition of volatile gas produced by each species of cells. Here, we developed the novel cancer recognition sensor suing virus-based structural color matrix. Due to its liquid crystalline behavior and surface modification ability, M-13 bacteriophage based color sensor exhibited remarkable selectivity and sensitivity to target samples including chemicals which compose VOCs of NCI. Upon exposure of small amounts of target molecules, the resulting colored matrices exhibited distinct different color changes that can be applied to effectively discriminate the target. Although the cancer cell sensing system was used as proof-of-concept in this study, this approach can be generalized to the detection of many harmful and biological toxicants. |
