| 초록 |
The combination of fluorescent carbon dots (FCD) and silver nanoparticles (AgNP) is effective for measuring antibacterial activity, but fluorescence quenching of FCD by AgNP is a limitation. In this study, we used poly(vinylpyrrolidone) (PVP) and catechol chemistry to bind AgNPs first and then bind FCD (PVP@Ag:FCD) to avoid fluorescence quenching of FCD and AgNP combinations. PVP@Ag:FCD undergoes electrostatic bonding with negatively charged bacterial surfaces and fluorescence quenching occurs through aggregation-induced fluorescence quenching. In addition, PVP@Ag:FCD achieved high bacterial killing even at low concentrations (0.1mg/ml). In real river water, PVP@Ag:FCD has shown effective performance for both detection and killing of bacteria. This work supported by Korea Institute for Advancement of Technology (KIAT) grant funded by the Korea Government (MOTIE) (P00008500, The Competency Development Program for Industry Specialist)
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