화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU))
권호 23권 2호
발표분야 포스터_콜로이드·계면화학
제목 Amine-Based Cationic Surfactants: Synthesis and Utilization of their Physical Properties to Prepare Liposomes
초록 Liposomes were prepared from cationic surfactants synthesized using three amines, namely triethylamine(TEA), tripropylamine(TPA) and tributylamine(TBA), and their antimicrobial activities were examined. The structures of the synthesized cationic surfactants were analyzed by Fourier transform infrared spectroscopy and proton nuclear magnetic resonance spectroscopy. The criticalmicelle concentration andsurface tension of the surfactantswere in the ranges1.9 ×10-3~8.1 ×10-4 mol/L and 16.2~25.7 dyn/cm, respectively. The resulting maximum surface excess concentration and minimum area per molecule were also reported. In addition, the foaming power and emulsion stability of the three synthesized surfactant types were measured. For the liposomes prepared using these surfactants, longer alkyl chains corresponded to larger-sized clean zones. TEA-16, TPA-16 and TBA-16 showed strong antimicrobial activity.
저자 조정은, 정노희
소속 충북대
키워드 Cationic Surfactant; Acyl Chloride; Liposome; Antimicrobial activity
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