| 학회 |
한국공업화학회 |
| 학술대회 |
2012년 가을 (10/31 ~ 11/02, 대전컨벤션센터) |
| 권호 |
16권 2호 |
| 발표분야 |
포스터-고분자 |
| 제목 |
Photo and PH-sensitive cationic vesicles prepared using N-[3-(Dimethylamino)propyl]-Octadecanamide and hexadecyloxy cinnamic acid |
| 초록 |
Vesicles composed of N-[3-(dimethylamino)propyl]-octadecanamide (DMAPODA) and hexadecyloxy cinnamic acid (HOCA) were prepared through melting and stirring after dissolving in distilled water. On micrographs, DMAPODA/HOCA molar ratios of 1:1 led to the formation of multilamellar vesicles. The mean size was around 1900nm. The Zeta potential of vesicles were around +35mV. Finally, photo-dependent changes in size and zeta potential were investigated on a particle size analyzer after ultraviolet irradiation at 365nm. The disintegration of vesicles was observed in acidic and alkali medium. This is due to that salt bridge may be destroyed at those conditions which caused the vesicles to be unstable. The vesicles might be used as photo-sensitive delivery carriers for therapeutic agents or genes. |
| 저자 |
차현주, Wang Min hui, 김진철
|
| 소속 |
강원대 |
| 키워드 |
cationic; surfactant; fatty acid; salt bridge; pH-sensitive; vesicles; |
| E-Mail |
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