| 초록 |
Biocompatible functional materials are essential for the implantable bioelectronics, particularly for the machine – tissue hybrid engineering. Among them, electrically conducting materials are one of the least biocompatible materials because conventional conductors such as metals and ceramics cause foreign-body reaction problems. To overcome this issue, naturally occurring conducting materials such as melanin, β-carotene, indigo, and tyrian purple are now receiving attentions as implantable biotic-abiotic electrode coating. Among them, we used natural melanin from Sepia officinalis ink and fabricated biocompatible conducting composites of melanin by layer-by-layer assembly (LBL) with polymers such as polyvinyl alcohol (PVA) and poly(diallyldimethylammonium) (PDDA). We further demonstrate the nanostructures, electrical properties, and biocompatibility of resulting composites by scanning electron microscope (SEM), electrochemical impedance measurement, and in vitro cell compatibility test with PC12 cell lines, respectively. |
