| 학회 |
한국재료학회 |
| 학술대회 |
2013년 가을 (11/06 ~ 11/08, 제주롯데호텔) |
| 권호 |
19권 2호 |
| 발표분야 |
제25회 신소재 심포지엄-조직재생 및 생체재료 심포지엄 |
| 제목 |
Application and degradation of electrospun alginate nanofibers for regenerative medicine |
| 초록 |
Alginate, a linear unbranched polysaccharide derived from seaweed that contains the repeating units of 1,4-linked β-D-man-nuronic acid and α-L-guluronic acid has shown great potential as a cell scaffold for the regeneration of many tissues, has only been nominally explored as an electrospun biomaterial for such applications due to cytotoxic chemicals that have typically been employed during both nanofiber formation and biopolymer crosslinking. And alginate is not naturally enzymatically degraded in mammals, ionically crossliked alginate hydrogels exhibit a remarkably slow degradation rate, which is typically months to years for their complete removal from injection site. Our laboratory recently developed electrospun cell adhesive peptide modified alginate, polyionic complexed chitosan-alginate, biodegradated alginate, and highly three-dimensional alginate nanofibers using electrospinning process. |
| 저자 |
Sung In Jeong1, Youn- Mook Lim2
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| 소속 |
1Research Division for Industry & Environment, 2Korea Atomic Energy Research Institute |
| 키워드 |
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| E-Mail |
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