| 초록 |
The development of stimuli-responsive materials with ability to alternate cell binding affinity in response to external signals has enabled the separation of engineered tissues from the culture platforms and the delivery of them into in vivo environment, called as scaffold-free cell delivery approach. Recently, we have developed cell-interactive and thermally expandable hydrogels for harvesting and delivering micro-tissues of various structures, from spheroids to multi-layered assembly. In this presentation, the applications of cell-interactive and thermally expandable hydrogels on fabrication and delivery of cells as a form of cell sheet, spheroids, micro tissue, and multiple-layered constructs with the use of various cell types including stem cells, endothelial cells, and fibroblasts will be discussed. |
