| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO)) |
| 권호 |
21권 2호 |
| 발표분야 |
고분자_포스터 |
| 제목 |
Near-infrared responsive monoolein cubic phase containing gold nanoparticles and polyethyleneimine/cinnamic acid conjugate |
| 초록 |
The positively charged polyethyleneimine (PEI) and the negatively charged cinnamic acid (CA) form conjugate by electrostatic interactions. Conjugates can form a self-assembly in aqueous phase because they exhibit amphipathic properties. Gold nanoparticles (GNP) are known to generate heat due to near-infrared surface plasmon resonance. As the temperature increases, the PEI/CA self-assembly loses its amphipathic property and disintegrates as the solubility of CA (the hydrophobic molecule) increases. The near-infrared responsive drug delivery vehicle was prepared by loading GNP and PEI/CA self-assembly on cubic phase. The cubic phase consists of a lipid bilayer and water channel, and this structure was observed through a transmission electron microscope. The release profile of fluorescent dye loaded on cubic phase was observed under near-infrared irradiation. |
| 저자 |
박단비, 김진철
|
| 소속 |
강원대 |
| 키워드 |
polyethyleneimine; cinnamic acid; gold nanoparticle; Near-infrared light
|
| E-Mail |
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