화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO))
권호 25권 1호
발표분야 포스터-콜로이드·계면화학
제목 Cholesterol-Functionalized Block-copolymers for Metal-Chelated Nanostructures with Enhanced Self-Assembly Efficiency
초록 We present an altered morphology of cisplatin-incorporated nanoparticles with cholesterol-functionalized double-hydrophilic block-copolymers (DHBCs).  Compared against the cholesterol-free counterpart, which generated a typical core/shell-structure with cisplatin-incorporated spherical core, cholesterol end group on the DHBCs leads to the formation of toroidal core inside the nanoparticle and allows for the density modulation of the metal-chelated core.  Additionally, the cholesterol-modification further enhanced the metal-mediated self-assembly efficiency of DHBCs by the enhanced hydrophobicity of cholesterol terminal ends.
저자 이상민
소속 가톨릭대
키워드 Cholesterol; Nanostructures; Self-Assembly; Block-Copolymers
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