학회 |
한국공업화학회 |
학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
권호 |
25권 1호 |
발표분야 |
포스터-콜로이드·계면화학 |
제목 |
Cholesterol-Functionalized Block-copolymers for Metal-Chelated Nanostructures with Enhanced Self-Assembly Efficiency |
초록 |
We present an altered morphology of cisplatin-incorporated nanoparticles with cholesterol-functionalized double-hydrophilic block-copolymers (DHBCs). Compared against the cholesterol-free counterpart, which generated a typical core/shell-structure with cisplatin-incorporated spherical core, cholesterol end group on the DHBCs leads to the formation of toroidal core inside the nanoparticle and allows for the density modulation of the metal-chelated core. Additionally, the cholesterol-modification further enhanced the metal-mediated self-assembly efficiency of DHBCs by the enhanced hydrophobicity of cholesterol terminal ends. |
저자 |
이상민 |
소속 |
가톨릭대 |
키워드 |
Cholesterol; Nanostructures; Self-Assembly; Block-Copolymers
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E-Mail |
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