| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 가을 (10/11 ~ 10/12, 일산킨텍스) |
| 권호 |
32권 2호 |
| 발표분야 |
생체모방형 고분자재료(의료용 고분자 부문위원회) |
| 제목 |
Fabrication and microstructure properties of biodegradable polycaprolactone (PCL)/cuttlebone (CB) scaffolds and their in vitro cellular study |
| 초록 |
Bone defects as a result of disease or injury have a very limited ability to heal spontaneously. Recently, tissue engineering has received considerable attention as a natural bone healing process. Hybrid scaffolds are one of the methods for bone regeneration technology. In this study, these hybrid scaffolds were fabricated with polycaprolactone (PCL) and cuttlebone (CB) by salt-leaching process. By using the sodium chloride (NaCl) as a pore-forming agent, porous PCL/CB scaffolds were fabricated by focusing on the volume percentages of CB and NaCl. In the porous scaffolds, pores in range of 200 – 300 μm in diameter were homogenously dispersed in the PCL/CB matrix and revealed excellent interconnected pores. The microstructures of these hybrid scaffolds were investigated by focusing on the mass ratio of CB and NaCl using SEM and ICP techniques. |
| 저자 |
임윤묵, 윤민호, 안성준, 김해경, 신준화, 이병헌, 노영창
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| 소속 |
한국원자력(연) |
| 키워드 |
polycaprolactone (PCL); cuttlebone (CB); hybrid; scaffold; bone graft substitute
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| E-Mail |
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