| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 20권 2호 |
| 발표분야 | 생물공학_포스터 |
| 제목 | Synthesis and in vitro characterization of 68Ga labeled Fe3O4 nanoparticles for drug delivery |
| 초록 | When the drug is uptake to the healthy cell, side effects such as vomiting and hair loss can be happen. Recently, nanoparticles (NPs) are the one of the most attractive drug delivery due to their enhanced permeability and retention (EPR) effect and it can minimize undesirable side effects. In this present work, nanocomposites were modified using Citric acid and Hydrazine. As this NPs be labeled with 68Ga, it can have dual applications as diagnostic imaging agent in positron emission tomography (PET) and magnetic resonance imaging (MRI). Also, Doxorubicin(DOX) as antineoplastic agent was loaded to the NPs for treatment of cancer. Thus 68Ga-Hydrizain-Citric acid-Fe3O4 NPs(68GaHFCNP) could exhibit synergic feature such as the magnetic behavior and radio activity for diagnosis and cytotoxicity for treatment. |
| 저자 | 문미미, 박승일, 김병철, 유국현 |
| 소속 | 동국대 |
| 키워드 | nano particle; drug delivery; Fe3O4 |
