| 초록 |
We report an indium triflate-catalyzed and lithium-mediated stereoselective intramolecular tandem conjugate addition of various nucleophiles to α,β-bisenones to afford a 1,2,3-trisubstituted six-membered ring bearing diketone substituents in good to excellent yields at room temperature. Various kinds of α,β-bisenones and nucleophiles were employed to expand the scope of this chemistry. Intramolecular trapping of metal-enolate by the tethered electrophiles resulted in the stereoselective formation of three contiguous stereogenic centers. |
