| 초록 |
A cicada wing has a feature of rupturing the membrane of cells, while the cactus spine transmit a water drop to the stem. Both of these properties have evolved from their unique structures. Here, we developed geometry-controllable polymer nanohairs that mimic the cicada‘s wing-like vertical hairs and the cactus spine-like stooped hairs. The cells on the vertical hairs showed significantly decreased proliferation while cells cultured on stooped nanohairs is strongly influenced by the direction of the stooped pattern. The cells on the flat structures showed random movement and the cells on the vertical nanohairs restricted the nanohair movement. However, cells on the stooped structure showed higher forward migration preference compared to that of the other structures. Consistent with these results, the vertical and stooped structures can facilitate the control of cell viability and guide directional migration for biomedical applications such as organogenesis. |
