| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Study on Immobilization of beta-Glucan in Chitosan Microspheres and Release Kinetics |
| 초록 |
Chitosan (CHN) is widely used as biomaterials due to its biocompatibility and biodegradability. CHN molecule, in particular, carries highly positive charges different from most of other biomolecules, which enables CHN to be used as a drug carrier. In this study, we prepared -glucan loaded CHN microspheres and evaluated the efficacy of drug loading and release pattern. The physicochemical properties of -glucan loaded CHN microspheres including size, surface charge, and surface morphology were examined using goniometer, scanning electron microscope. The drug release kinetics was evaluated using high performance liquid chromatography. The effects of drug release on the growth and differentiation of osteoblastic cells were characterized via cellular assays. This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717 ） |
| 저자 |
xumengcan1, Sasithorn Kongruang2, Fah Kudou2, 박진우1, 이지현1, 이우걸1
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| 소속 |
1단국대, 2King Mongkut's Univ. of Technology North Bangkok |
| 키워드 |
Chitosan; β-glucan; microsphere drug release
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| E-Mail |
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