| 초록 |
Nitrilotriacetic acid (NTA) is a well-known tetradentate ligand capable of occupying four positions in coordination sphere of octahedral metals. When NTA is complexed with octahedral metals, such as Ni2+, it has strong interaction with a sequence of histidine residues in the proteins. This interaction can be controlled by addition of competing ligands, e.g. imidazole. Therefore, the introduction of NTA group at the polymer chain end can be an attractive of approach for bio-conjugation of polymers with proteins. In this presentation, I will discuss the preparation, characterization and applications of (nitrilotriactic acetic acid)-end-functionalized polymers which was prepared via Atom Transfer Radical Polymerization (ATRP). |
