| 초록 |
The fission yeast Schizosaccharomyces pombe, is one of two yeast systems that have been central in the study of higher eukaryotes, the other being Saccharomyces cerevisiae, as a model system. Physiological similarities in cell division between S. pombe and mammalian cells and genetic similarity of several genes found in human have made S. pombe and important model system in elucidating higher eukaryotic function. The genome-scale metabolic model maps the metabolic network of S. pombe which allows for a more better understanding and study of the metabolism behind the observed physiology. This tool further allows for prediction of novel physiological characteristics, given a set genetic perturbation linked to the metabolic network. As a result, insights into the metabolic physiology of S. pombe, can be examined and applied towards the improvement of human life. |
