| 초록 |
We developed a generalized synthetic procedure, called heat-up process, to produce uniform-sized iron oxide nanocrystals with controlled sizes ranging from 1.5 nm to 100 nm. High resolution blood pool magnetic resonance (MR) imaging using uniform 3 nm-sized iron oxide nanoparticles enabled clear observation of various blood vessels with sizes down to 0.2 mm. We used 80 nm-sized ferrimagnetic iron oxide nanocrystals for T2 MRI contrast agent for tracking transplanted pancreatic islet cells and single-cell MR imaging. We reported on the fabrication of monodisperse magnetite nanoparticles immobilized with uniform pore-sized mesoporous silica spheres for simultaneous MRI, fluorescence imaging, and drug delivery. |
