| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Preparation and characterization of encapsulated drug with poly(ε caprolactone)/poly(ethylene oxide) microcapsule |
| 초록 |
Microcapsules were prepared by a solvent evaporation using a water/oil/water (W/O/W) emulsion system. W/O emulsion consist of an aqueous solution containing rhodamine B as hydrophilic drug and a dichloromethane solution of containing biodegradable polymers such as hydrophobic poly(ε-caprolactone) (PCL) and hydrophilic poly(ethylene oxide) (PEO). The W/O emulsion was added to another aqueous solution containing 0.006%(w/v) PVA. The microcapsule was investigated by scanning electron microscope (SEM), Fourier transform infrared spectroscope (FT-IR), and confocal laser scanning microscope (CLSM). The release of rhodamine B from the PCL/PEO microcapsules was investigated by UVVis spectroscope. PCL/PEO microcapsules showed higher release of rhodamine B as PEO content increased due to the higher hydrophilicity of microcapsule components. |
| 저자 |
오애리, 윤주미, 김형일
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| 소속 |
충남대 |
| 키워드 |
W/O/W emulsion system; poly(ethylene oxide); poly(ε-caprolactone)
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| E-Mail |
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