화학공학소재연구정보센터
학회 한국재료학회
학술대회 2016년 가을 (11/16 ~ 11/18, 경주 현대호텔)
권호 22권 2호
발표분야 B. 나노화학/바이오 재료 분과
제목 Rylene Dye-Loaded Probe Nanoparticles for Visible-Infrared Imaging
초록 Rylene dyes exhibit superior photophysical properties including outstanding chemical and photochemical stabilities as well as high fluorescence quantum yields (FQYs). However, the rylene chromophores are highly hydrophobic to use them as biological molecular probes unless functionalized to ensure water-solubility. We present a general incorporation method to load rylene family within micelle core of triblock copolymer and stabilize the core. The polymer-encapsulated rylene dyes in confined hydrophobic environment fairly preserve their FQYs in aqueous media. Twenty one probe nanoparticles (PNPs) loaded with rylene dyes, in the spectral region of visible and infrared (400 – 750 nm) were prepared and their photophysical properties were characterized. The PNPs may pave the way for a new class of fluorescence probes applicable in in vitro and in vivo imaging.
저자 Mingyeong Kang1, Chen Li2, Klaus Müllen3, Minseok Kwak4
소속 1Department of Chemistry, 2Pukyong National Univ., 3Busan 48513, 4Korea
키워드 <P>perylene; terrylene</P>
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