화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO))
권호 25권 2호
발표분야 포스터-생체재료
제목 Enzyme guided site-specific fabrication of multifunctional polycatecholic pigment for cell manipulation
초록 Surface modification techniques allows to control the interfacial behavior of substrates while maintaining their bulk properties. However, spatial control of the surface modification often require mask and/or microfluidic channel fabrication, which are labor-intensive and raise the cost issues. Recently, ink-jet printing has been emerged as alternatives to these techniques due to their conveniency in spatial control without any template. Herein, we report that horseradish peroxidase (HRP) can be an efficient ink that guide the site-specific growth of multifunctional polycatecholic pigment on local area. Given the unique adhesive properties of catecholic moieties, it was observed that the HRP-mediated synthesized pigment was attached nearby HRP without diffusion into the solution where precursors are dissolved in. The fabricated pigments exhibited good biocompatibility, promoted cell adhesion, and possessed high photothermal conversion efficiency like natural melanin.
저자 정해진, 홍선기
소속 대구경북과학기술원
키워드 catechol; biopigmentation; melanin; ink-jet printing; horseradish peroxidase
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