화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center))
권호 24권 1호
발표분야 포스터-생체재료
제목 Novel stem cell therapy using blue light based photobiomodulation for improving angiogenesis in mouse hindlimb ischemia
초록 Photobiomodulation has drawn attention as a new method for enhancing therapeutic efficacy in various diseases. We introduced blue organic light emitting diode as a safe and effective light source compared to the conventional light emitting diode and laser. In this study, we tried to investigate the most efficient properties such as wavelength and light fluence that can improve therapeutic angiogenesis. Based on our research, optimized blue light, improved angiogenic efficacy of human adipose derived stem cells (hADSCs) without phototoxicity. Ischemic tissue damages were decreased and angiogenesis was significantly increased when hADSCs with blue light treatment were transplanted to the ischemic animal model.
저자 현지유, 방석호
소속 성균관대
키워드 photobiomodulation; blue light; ischemic disease; stem cell
E-Mail