화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크)
권호 13권 2호
발표분야 정밀화학(포스터)
제목 Synthesis of Biocompatible Manganese ferrite Nanocrystals for Conjugation with Cell Targeting Agents
초록 Preparation of biocompatible water dispersible superparamagnetic manganese ferrite (MnFe2O4) nanocrystals by one-pot thermal decomposition reaction of metal acetylacetonate precursor was studied. Polyethylene glycol diacid was used as a steric stabilizer and surface capping agent. We have achieved these carboxylic acid functionalized nanocrystals coupled with 9-aminoacridine and folic acid using carbodiimide. Based on this exploration, we believe this novel synthetic approach will pave a new way for the preparation of water-soluble MnFe2O4 nanocrystals and provide a potential candidate of high quality nano-platform in MR imaging and drug delivery system.
저자 록치충, 채규윤
소속 원광대
키워드 superparamagnetic manganese ferrite; one-pot reaction; PEG
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