| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
23권 2호 |
| 발표분야 |
포스터_생체재료 |
| 제목 |
Synthesis and drug release properties of allopurinol imprinted functional transdermal patch using MBS, PVA, and melanin nanoparticle |
| 초록 |
In this study, functional transdermal patch was prepared by MBS, PVA, melanin nanoparticle (MEL-NP), allopurinol (ALP), and glycerol. The characterization and physical properties of prepared transdermal patches with/without the addition of MEL-NP and ALP were investigated. MEL has a high photothermal conversion efficiency under 808 nm NIR laser irradiation. Therefore, the effects of drug release on a transdermal patches added MEL-NP can be enhanced by NIR laser irradiation. The solution of temperature containing transdermal patches added MEL-NP increased from 25 oC to 40 oC by NIR irradiation for 5 min. The release of ALP was rapidly increased from transdermal patches added MEL-NP with irradiation of NIR when compared with transdermal patches without MEL-NP and without NIR irradiation. From the results, we suggest that the prepared functional transdermal patches can be applied as a biomedical material for the acute treatment and localized drug release. |
| 저자 |
김한성, 이민우, 윤순도, 이창문, 정헌호, 변헌수
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| 소속 |
전남대 |
| 키워드 |
Functional transdermal patch; Melanin nanoparticle; Allopurinol; Release properties
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| E-Mail |
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