| 초록 |
The metal patterned substrate containing the periodicity of an ensemble of metal nanostructures is an important parameter for the resonant field enhancement, since highly ordered metal nanostructure is far greater than that of aperiodic array or randomly roughened metal surface. As yet, however, few attempts have been made in the use of metal nanopattern as the MEF, largely due to the difficulty of generating perfect nanoarrays with millimeter dimension and placing and immobilizing the biomolecules at predefined positions afforded by the periodic regions of the templates. Here, we fabricated a platform of the use of large-area of metal nanopattern using capillary lithography with high-throughput for fluorescence enhancement in a form of biomolecular sensing array. To implement our strategy, we used capillary force lithography to fabricate nanopatterns with various feature sizes on large patterned area. Flexibility of generating various pattern sizes from a single prepattern makes this approach very attractive, and it has significant advantage of low cost and high-efficiency. The feature dimension variations of the resultant patterns are also obtained from the masters with many different dot sizes, periods and height.We show that the feature dimension of the large-area gold patterns strongly affects the sensitivity of the biomolecules. This approach to controllable patterning is potentially useful in the fabrication of unique nanopatterns or nanostructures without the need for complicated and expensive methods. We also discuss other supramolecular self-assemblies such as liquid crystals and dendrimers for the fabrication of nano-scale patterns and their potential applications in opto-electronics. |
