학회 | 한국재료학회 |
학술대회 | 2021년 가을 (11/24 ~ 11/26, 경주 라한호텔) |
권호 | 27권 2호 |
발표분야 | 특별심포지엄 5. 첨단 메타물질 심포지엄-오거나이저: 한성옥(KIER), 이학주(KIMM) |
제목 | Advanced Terahertz Metamaterials and Applications |
초록 | Terahertz (THz) electromagnetic waves enhanced by nanometer-scale metal structures significantly increase interaction with matter within the near-field. In particular, metamaterials with specially patterned nanoslot structures provide a high electric field enhancement and resonance effect at specific THz frequency, can be optimized for intrinsic biochemical molecular vibrational modes. The THz metamaterial based sensing devices can be fabricated by typical photolithography and general semiconductor processes, which enables large-area imaging for bio samples as well. Also, two-dimensional imaging with highly enhanced image contrast will be introduces for wide range of bio- and medical-applications. Using this technology, a protein called amyloid beta plaque, which exists in trace amounts in the brain and is known to cause dementia was observed in mouse brain tissue [1-3]. In the conventional imaging method, only relative comparisons were possible based on the difference in brightness and darkness of images even using fluorescence, but because terahertz waves are sensitive to the state of molecules, the amount of amyloid beta proteins accumulating in the brain could be imaged as the disease progresses, and quantitatively analyzed in a label-free manner. - References [1] Sang-Hun Lee, Seulgi Shin, Yeeun Roh, Seung Jae Oh, Soo Hyun Lee, Hyun Seok Song, Yong-Sang Ryu, Yun Kyun Kim, and Minah Seo*, “Label-free brain tissue imaging using large-area terahertz metamaterials,” Biosensors and bioelectronics 112663 (2020). [2] Minah Seo* & Hyeong-Ryeol Park*, “Terahertz Biochemical Molecule‐Specific Sensors,” Advanced Optical Materials 1900662 (2020). [3] Sang-Hun Lee, Jong-Ho Choe, Chulki Kim, Sukang Bae, Jin-Soo Kim, Q-Han Park, Minah Seo*, “Graphene Assisted Terahertz Metamaterials for Sensitive Bio-sensing,” Sensors and Actuators B: Chemical 310, 127841 (2020). Acknowledgements This work was supported in part by KIST intramural grants (2E31271). M.S. acknowledges the support from the National Research Foundation of Korea (NRF) (NRF-2020R1A2C2007077 and the Global Frontier Program CAMM-2019M3A6B3030638). |
저자 | 서민아 |
소속 | 한국과학기술(연) |
키워드 | <P>Terahertz Metamaterials; Bio-sensors; Metamaterial Applications</P> |