| 초록 |
For the early detection of bacterial infection in several conditions, demands on fast and cheap detection methods of bacteria in biomedical science are increasing. However, while current bacterial detection methods such as microbial culture, and molecular diagnosis are sensitive enough, show limitations in time and simplicity. In this study, we first introduce a concept of a simple and fast assay using carbon dot nanoparticles with fluorescence, which can be switched on and off depending on the presence of bacteria as the target. Conducting the assay just requires the mixing of the carbon dot solution with dopamine along with the sample including bacteria. Fluorescence signal turned off with polydopamine formation while the existence of bacteria caused signal to turn on. With further research, this method can be applied as the simple and fast diagnosis of bacteria, without using expensive methods for bacterial detection. |
