| 초록 |
The using of medical gas released from the stable coating surface provides advantageous absence of residual product in the body. However, controlling therapeutic gas molecule from solid materials is challenging research because a rapid gas release rate can be harmful to the body. Nitric oxide (NO) gas plays a role in various treatments depending on its concentration. It is a free radical gas resulting in low stability and short life. To overcome the limitations, the combination of amine-functionalized graphene oxide (fGO) and graphene oxide (GO) film was introduced. The multilayer structure increases the length of the diffusion path and created a low gas permeability film. Furthermore, the presence of intra-hydrogen bonding from the amine group on fGO sheet acts as a NO gas stabilizer. Finally, the multilayer films were applied for cell-migration and anti-inflammation tests. As a consequence, we conclude that the multilayer film loading NO gas exhibited a good effect on wound healing. |
