화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터)
권호 37권 2호
발표분야 기능성 고분자
제목 Direct-write Patterning of Bacterial Cells by Dip-pen Nanolithography
초록 The ability of dip-pen nanolithography (DPN) to generate nano- or micro-arrays of soft or hard materials (e.g., molecular inks, DNA, proteins, nanoparticles, sols, and polymers) with a direct-write manner has been widely demonstrated. This technique, however, remains a challenge in transporting large sized ink materials such as bacteria. The size limitation of water meniscus formed between the tip and the solid surface becomes a bottleneck in such diffusion-based molecular transport experiments. In this work, we report a straightforward “stamp-on” DPN method that uses a nano-network poly(2-methyl-2-oxazoline) hydrogel coated tip and carrier agents to generate patterns of micrometer sized Escherichia coli JM 109 bacterial cells. We demonstrate that this approach enables one to deposit a single bacterial cell array on a solid surface or layer multiple cells array by varying the viscosity of the “ink” solution.
저자 김지은, 오신석, 황인설, 김아라, 김경민, 임정혁
소속 한국교통대
키워드 dip-pen nanolithography; E. coli bacteria
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