| 학회 |
한국고분자학회 |
| 학술대회 |
2016년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
| 권호 |
41권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Nanobiomaterials potentiate stem cell-mediated tissue regeneration |
| 초록 |
Nanobiomaterials can direct stem-cell fate both in vitro and in vivo by displaying stem-cell-regulatory signals in a precise fashion. Graphene and its derivatives can promote adsorption of cell-adhesion signals and soluble signals, which can be applied to enhancement of differentiation of mesenchymal stem cells (MSCs) into chondrogenic lineages. Nanobiomaterials can provide co-culture platforms for the generation of lineage-specific cells differentiated from MSCs that exceed the therapeutic potentials of non-modified MSCs. Graphene and its derivatives can serve as a cellular adhesive to prevent reactive oxygen species-mediated death of MSCs implanted to ischemia-damaged and reperfused myocardium and also can potentiate the myocardial repair efficacy of MSCs through stimulating expression of angiogenic growth factors and gap junction protein. |
| 저자 |
김병수 |
| 소속 |
서울대 |
| 키워드 |
nanobiomaterial; stem cell; tissue regeneration
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| E-Mail |
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