초록 |
Graphene is defined as a one-atom thick, planar monolayer of carbon atoms arranged into a two-dimensional honeycomb crystal lattice. As with many novel materials, applications of graphene and its family nanomaterials, such as graphene oxide (GO) and reduced GO, offer various technological opportunities since they exhibit exceptional electrical, thermal, optical and mechanical properties. The practical uses of graphene and its derivatives are extensive, including applications as diverse as nanoelectronics (e.g. transistors and sensors), anti-bacterial paper and many biomedical uses such as drug delivery, diagnosis and therapy. Recently, much attention has been paid to the potential of graphene-based materials as factors promoting osteogenic and neuronal differentiation of mesenchymal and neural stem cells (SCs), respectively. Studies, in particular, have endeavored to determine the behavioral changes of SCs on a specific substrate coated or patterned with graphene or its derivatives. In this presentation, we discuss the biocompatibility and biofunctionality of graphene-based nanobiomaterials and their potential applications for scaffolds beneficial to neurogenesis and osteogenesis. |