| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Surface-initiated ring opening polymerization (SI-ROP) of L-Lactide onto metal stent for enhancing interfacial adhesion |
| 초록 |
Method of securing the adhesion of biodegradable polymer coating was investigated for stent applications, using a SI-ROP of L-lactide. The thickness of the polymer grafted on stainless steel (SS) remained in nanometer scale, as determined by using ellipsometer, ATR-FTIR, and ESCA. To measure the adhesive forces, PLGA was coated on the different substrates - intact SS, plasma-treated SS, and L-lactide-grafted SS (nanocoupled SS) - using electrospraying and these groups were tested for their adhesion forces using a scratch tester. The results exhibited that the nanocoupled SS was most adhered with the coating polymer as compared to other groups. This work suggested that interfacial adhesion stability considerably increased by utilizing the concept of nanocoupling but the drug release from polymer coating was rarely affected. |
| 저자 |
조성배1, 박귀덕1, 이봉수1, 최지연1, 정동준2, 한동근1
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| 소속 |
1한국과학기술(연), 2성균관대 |
| 키워드 |
stent; ring opening polymerization; L-Lactide; nanocoupling
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| E-Mail |
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