| 초록 |
The versatile medical coatings in the biomedical field alleviates patient pain and economic burdens. Layer-by-layer (LbL) assembly is an excellent coating technique for medical materials in that a coating can be prepared using various materials, regardless of the size and shape of the substrate. In this study, we fabricated polysaccharide-based multilayer films using carboxymethyl cellulose and chitosan as materials for LbL assembly. Furthermore, by introducing chemical crosslinking into the assembled multilayered film, the coating was given superhydrophilicity with antibacterial effect. This coating not only exhibited excellent stability in various acidic and enzymatic environments, but also served as a drug delivery carrier. We applied this coating to dental and ophthalmic materials and performed various experiments and analyzes for practical use. We attempted to accumulate datasets for our nano-coating design and to develop sophisticated methods to assess nanoscale changes. |
