| 학회 |
한국고분자학회 |
| 학술대회 |
2020년 가을 (10/05 ~ 10/08, 부산컨벤션센터(BEXCO)) |
| 권호 |
45권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Modular Protective Nanoporous Polyurea Network Membranes for Enzymatic Catalysis |
| 초록 |
Immobilization in porous solid supports are commonly employed for enzymes, while various nanoporous structures have shown additional benefits such as shielding against deactivation agents. However, a few reports employed bicontinuous nanoporous membrane for enzyme protection and efficient enzymatic functions simultaneously. Recently, we reported caging lipase in nanoporous covalent polymer membrane prepared from the poly (ethylene glycol)/poly-urea network mixtures. Facile membrane preparation and enzyme loading by filtration and improved lifespan compared to free enzyme. To broaden the scope of the enzymes and examine the protective effects of confinement on the activity of enzymes, we studied the enzymatic reactions by other categories of enzyme. The effect of confinement on enzymatic kinetics and shielding efficiency were thoroughly investigated to prove the general applicability of caging in the bicontinuous nanoporous structure. |
| 저자 |
오왕석1, 박지웅2
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| 소속 |
1광주과학기술원, 2광주과학기술원 신소재공학부 |
| 키워드 |
nanoporous polymer; membrane; enzymatic catalysis; organic sol gel synthesis
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| E-Mail |
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