| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Implantable Photothermal Agents of Gold Nanorods encapsulated Polymer Microcube |
| 초록 |
Gold nanorods (GNRs) have received much attention in photothermal therapeutics by virtue of enhanced NIR absorbance with increased cross-sections, tunable optical properties by adjusting aspect ratios, and facile preparation by well-established synthesis methods. However, the intrinsic problem of nanoparticles, the nanotoxicity, pose a question of photothermal therapy using nano-sized photothermal agents. Herein, we present a method encapsulating GNRs into PEG based microcubic polymer networks via stop flow lithography. This microcubes have two notable properties: (1) The microcubes can be implanted at a specific site with relatively large size maintaining similar optical properties and photothermal effects compared to bare GNRs. (2) GNRs can be immobilized in microcubes, preventing the potential toxicity of GNRs. Overall, In vivo experimental results support these properties of GNRs encapsulated microcubes. |
| 저자 |
문현준1, 구민희2, 이현지1, 윤나라2, 문석준1, 양재문2, 봉기완1
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| 소속 |
1고려대, 2연세대 |
| 키워드 |
Microparticles; Implantable photothermal therapy; Gold nanorods; hydrogels
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| E-Mail |
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