| 학회 |
한국화학공학회 |
| 학술대회 |
2019년 봄 (04/24 ~ 04/26, 제주국제컨벤션센터) |
| 권호 |
25권 1호, p.664 |
| 발표분야 |
이동현상(Transport Phenomena) |
| 제목 |
Gold Nanorods-Encapsulated Implantable Microcube for Photothermal Therapy |
| 초록 |
Gold nanorods (GNRs) have received much attention in photothermal therapeutics by virtue of enhanced NIR absorbance with increased cross-sections, tunable optical properties by adjusting aspect ratios, and facile preparation by well-established synthesis methods. However, the intrinsic problem of nanoparticles, the nanotoxicity, pose a question of photothermal therapy using nano-sized photothermal agents. Herein, we present a method encapsulating GNRs into PEG based microcubic polymer networks via stop flow lithography. This microcubes have two notable properties: (1) The microcubes can be implanted at a specific site with relatively large size maintaining similar optical properties and photothermal effects compared to bare GNRs. (2) GNRs can be immobilized in microcubes, preventing the potential toxicity of GNRs. Overall, In vivo experimental results support these properties of GNRs encapsulated microcubes. |
| 저자 |
문석준1, 봉기완1, 문현준1, 구민희2, 이현지1, 양재문2, 윤나라2
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| 소속 |
1고려대, 2연세대 |
| 키워드 |
이동현상 |
| E-Mail |
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| 원문파일 |
초록 보기 |
