| 초록 |
It is evident that all animals have developed on Earth in a pre-existing microbial world and thus have coevolved with constant interactions with microbes. In particular, alimentary canals of all animals are colonized by different microbial cells (i.e. gut microbiota). The critical role of gut microbiota and its associated genome (i.e. gut microbiome) in organismal homeostasis is becoming increasingly evident because a number of studies have validated the effects of an altered gut microbiota on obesity, nutritional deficiencies, diabetes, cardiovascular disease, inflammatory disease, and brain function. Such diverse implications of the gut microbiome in animal health and diseases provide a novel insight into the understanding, prevention, and the possible remedies of these important diseases. We will discuss recent findings on the effects of gut commensal microbes on human health and disease. |
