| 초록 |
Medical materials are used to diagnose and treat diseases, and to replace damaged body parts or promote regeneration. Such materials should not elicit any side effects or an immune rejection response. Moreover, they should be able to sustain the function of materials without degradation for appropriate periods according to the therapeutic purpose. Natural polymers have low immune rejection responses and excellent biocompatibility, and can be applied to various medical fields. To immobilize drugs using natural polymer, photo-immobilization method has been designed. For photo-immobilization, photo-reactive functional group should be introduced to natural polymer. According to purpose of application, you could choice one of the photo-reactive functional group. Natural polymers include gelatin, alginate and chitosan; such polymers have been used to improve cell affinity and tissue adhesion, and have been used in coating materials for implants and stents, and in drug delivery systems. |
