| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
고분자 합성 |
| 제목 |
Dendritic poly(ethylene glycol) by aninoic ring opening polymerization |
| 초록 |
Anti-fouling materials are important to prevent the absorption of non-specific proteins at the surface of for implanted biomaterials and biosensors. Poly(ethylene glycols)(PEG) is a representative anti-fouling materials. Peglyated protein is an example of application PEG to drug delivery systems. To improve anti-fouling effect of PEG, dendritic poly(ethylene oxide)s were synthesized by anionic polymerization of ethylene oxide from three hydroxylated branching point of PEO chain ends. We employed an initiating system composed of allyl alcohol as an initiator and DPMK as electron transfer agents in THF. The initiating system was suitable for a “controlled/living” polymerization of ethylene oxide at room temperature. The sequences of reactions allowed us to prepare a dendritic PEGs up to a higher generation. All generations are characterized by 1H NMR spectroscopy, GPC and MALDI-TOF. |
| 저자 |
허정윤1, 안철희2, 김정안3
|
| 소속 |
1서울대, 2서울대 공과대, 3경희대 |
| 키워드 |
anionic polymerization; poly(ethylene oxide)s
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| E-Mail |
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