| 학회 |
한국공업화학회 |
| 학술대회 |
2010년 봄 (05/13 ~ 05/14, BEXCO(부산)) |
| 권호 |
14권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Preparation and characterization of Pullulan-g-Poly(L Lysine) copolymer as an efficient gene delivery carrier |
| 초록 |
Recently, researches on the non-viral gene delivery have focused on the development of efficient gene carriers with excellent safety profiles. Polypeptide/polysaccharide graft copolymers poly(L-lysine)-graft Pullulan(Pul-g-PLL) were prepared by ring opening polymerization of ε-benzoxycarbonyl L-lysine N-carboxyanhydride (Z-l-lysine NCA) in the presence of Pullulan(Pul). The physicocheical properties of the Pul-g-PLL copolymer were investigated by using IR, 1H-NMR, Dynamic light scattering and Spectrofluorophotomerer. The PUL-g-PLL copolymer was investigated to efficient gene carrier. |
| 저자 |
박준규1, 홍락준1, 이경재1, 최창용1, 박윤경2, 나상권3, 장미경1, 나재운1
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| 소속 |
1순천대, 2조선대, 3다이나믹(주) |
| 키워드 |
Pullulan; poly Lysine; gene carrier
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| E-Mail |
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