| 초록 |
For many years, we have conducted research on modifying the surface with polymeric coatings that contains weak polyelectrolytes, which are pH- and ionic strength-responsive, water-soluble polymers. Some of the coatings include metal nanoparticles those created in polymer-hybrid systems. These organic-inorganic hybrid materials revealed multiplexed properties that may be applied as a novel material for biomedical and/or environmental engineering fields. For those applications, an excellent biocompatibility or no cytotoxicity may be the most important property of the coating. Therefore, we examined biocompatibility of the materials, and furthermore, studied the cellular responses including adhesion, proliferation, motility on the coatings. Throughout the study, we utilized layer-by-layer deposition method which allowed to create nano-scaled composite materials. The characteristics of the environmental-resposive polymers were extra attributes of this system which allows us to explore various results in their film surface properties. |
