화학공학소재연구정보센터
학회 한국재료학회
학술대회 2013년 가을 (11/06 ~ 11/08, 제주롯데호텔)
권호 19권 2호
발표분야 D. 바이오재료(Biomaterials)
제목 The evaluation of collagen coated cow bone graft materials for bone tissue engineering
초록  The demineralized cow bone coated collagen type I was developed to investigate the effect of both with and without collagen coated cow bone for bone tissue engineering. Cow bone scaffolds were demineralized by DBM method and evaluated by scanning electron microscope (SEM), mercury porosimetry and X-Ray Diffraction (XRD). The in vitro evaluation of cow bone and collagen coated scaffold was done by MTT assay, BCA assay, Live/dead cell and immunofluorescent using mouse calvaria-derived preosteoblastic cells (MC3T3-E1). The collagen coated cow bone show the ability for supporting the cells proliferation and gene expression. Compare with original cow bone, the cow bone- collagen scaffold could be better for bone regeneration application.
저자 Kim Ji Hyun1, Nguyen Thuy Ba Linh2, Young Ki Min1, Byong Taek Lee2
소속 1Department of Regenerative Medicine, 2Soonchunhyang Univ.
키워드 Cow bone; DBM; Collagen type I
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