| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
(정밀화학) 정밀화학기술의 최신 연구동향 및 응용 |
| 제목 |
Development of reliable radiolabeling strategies specifically for clinical setting |
| 초록 |
Positron emission tomography (PET) is a non-invasive imaging modality used for in vivo monitoring of radioligand distribution and concentration. Various radioisotope labeling methods have become common due to the widespread availability of affordable cyclotrons in clinics. Fluorine-18 is a positron emitter with a half-life of only 110 min. New rapid radiofluorination chemistries are required to expand the application of PET tracers in early detection and monitoring of disease progression. To meet the high demands of these applications, an expeditious radiolabeling protocol that can be applied to both simple PET radiopharmaceuticals and complex biomacromolecules is required. The application of radiofluorination technology with hypervalent aryliodine compounds significantly expands the number of possible radioligands to use in PET imaging for clinical research and drug development. |
| 저자 |
전중현 |
| 소속 |
연세대 |
| 키워드 |
Positron emission tomography (PET); Fluorine-18; Radiofluorination; Radiophamaceutical
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| E-Mail |
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