| 초록 |
Ice recrystallization inhibitors (IRI) are of great importance in cryopreservation of cells, tissues, organs, and food. In recent studies, amphipathic glycoprotein with segregated hydrophobic/hydrophilic groups mimicking antifreezing glycoproteins (AFGPs) emerged as an promising compounds with IRI and ice nucleation inhibition (INI) activity. The balance of hydrophobic and hydrophilic moieties in a molecule plays an important role in IRI activities. Here, we compared between thymine-20mer and uracil-20mer for differences in IRI activity, non-colligative depression of the freezing point (thermal hysteresis), dynamic ice shaping, and ice nucleation inhibition. |
