| 학회 |
한국화학공학회 |
| 학술대회 |
2007년 가을 (10/26 ~ 10/27, 한국과학기술원) |
| 권호 |
13권 2호, p.1697 |
| 발표분야 |
생물화공 |
| 제목 |
Development of Biomemory Consist of Recombinant Redox Protein using Site-Directed Mutagenesis |
| 초록 |
Molecular electronics has been a key trigger for driving significant scientific and technological advance in current memory device. For making efficient bioelectronic device, we have developed novel immobilization method of cupredoxin azurin modified on gold surface. A recombinant protein with cysteine residue by using Site-Directed Mutagenesis was designed and then directly immobilized on Au surface without any chemical linker. We confirmed immobilization by Surface Plasmon Resonance and Scanning Tunneling Microscopy. And ‘Write’, ‘Read’, and ‘Erase’ functions of self assembled azurin were investigated by redox reaction of metalloprotein by using Cyclic Voltammetry and Open Circuit Potential Amperometry. These results could be applied to fabricate molecular memory device using redox ability of cysteine-modified azurin. Acknowledgments : This research was supported by the Nano/Bio science & Technology Program (M10536090001-05N3609-00110) of the Ministry of Science and Technology (MOST), by the Korea government (MOST) (2006-05374), and by the Korea Research Foundation Grant funded by the Korean Government (MOEHRD) (KRF-2006-005-D00003). |
| 저자 |
김상욱1, 김영준1, 김순중1, 이상백2, 오병근1, 최정우1
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| 소속 |
1서강대, 2제주대 |
| 키워드 |
Molecular Electronic; Surface Plasmon Resonance; Scanning Tunneling Microscopy; Cyclic Voltammetry; Open Circuit Potential Amperometry
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| E-Mail |
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| 원문파일 |
초록 보기 |
