| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터) |
| 권호 |
36권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Effect of Crosslinking Agent CaCl2 on the Proliferation and Phenotype of Retinal Pigment Epithelial Cells on Alginate Films. |
| 초록 |
The retinal discords in which it shows up while an age gives is caused by a heredity. Thus, transplantation of cell in human needs a suitable scaffold. One of the scaffolds, alginate is currently proved to be biological safe. It is identified for producing Ca2+ cross-linked thin films of sodium alginate, using an 0.4, 0.6. 0.8M CaCl2 solution. RPEs were seeded into 1% alginate films. After 1, 3 and 7days of cell seeding, cell proliferation and viability were measured via MTT assay. In addition, morphology of cellular adhesion by SEM. RT-PCR was conducted to confirm mRNA expression of RPEs markers. We confirmed that cell viability on Alginate films of 0.6M were higher than other films. This research was supported by WCU (R31-20029) and XRC (A040004). |
| 저자 |
이가영, 조은혜, 유한나, 강수지, 이동원, 강길선
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| 소속 |
전북대 |
| 키워드 |
Pigment Epithelial Cells; Alginate
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| E-Mail |
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