| 초록 |
Water soluble β-cyclodextrin (β-CD) polymers were synthesized using native β-CDs with a cross-linker of epichlorohydrin (EPI) in NaOH solution (33%, w/w). Since cyclodextrins are capable to form the inclusion complexes with ring structure chemicals, the cationic compounds named trimethylammonium chloride benzoate (TMACB) was included into the cavities of CDs. After modified poly(β-CD), a natural anionic polymer carboxymethyl cellulose (CMC) was used to form microgel with poly(β-CD) by taking advantage of salt bridge between the amino group of TMACB and carboxyl group of CMC. In our study, the poly(β-CD) was analyzed by NMR, and the content of CD in polymer was determined using phenolphthalein. And the microgels were investigated on TEM, SEM, and particle size analyzer. According to the results, the water soluble poly(β-CD) was successfully synthesized, and the release of FITC-dextran from microgels depends on the pH due to the deionization of carboxyl groups in CMC. |
