| 학회 |
한국공업화학회 |
| 학술대회 |
2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 |
24권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Titanium-tethered cell-derived lipid bilayer with selenium catalyst to achieve a permanent NO releasing system |
| 초록 |
Extracted cell membranes derived lipid bilayers is currently promising strategy in biomedical systems due to its biocompatibility and versatility. In this study we fabricated a tethered lipid bilayer (TLB) system, with membranes extracted from endothelial cells, on titanium and embedded a synthesized selenium catalyst that mimics nitric oxide synthase (NOS) to achieve a continuous NO releasing system from metallic surfaces. Surface analysis techniques unveiled successful formation of the TLB with acceptable surface coverage. In vitro cell studies showed superior endothelial cell attachment and proliferation and inhibition of smooth muscle cell growth in comparison with bare titanium and artificial TLB that was prepared with synthesized phospholipids. |
| 저자 |
Md Lemon Hasan, Mahmoud A. Elnaggar, 정윤기
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| 소속 |
한국과학기술(연) |
| 키워드 |
lipid bilayers; tethered lipid bilayer (TLB); NO releasing system
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| E-Mail |
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