| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO)) |
| 권호 |
25권 2호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Cell-derived tethered lipid bilayer for a cell culture platform |
| 초록 |
Tethering lipid bilayers derived from cell membranes on a substrate is a currently emerging strategy in biomedical systems due to their versatility. In this study, we fabricated a tethered lipid bilayer (tLB) on titanium using membranes from endothelial cells. Synthetic selenium catalyst was embedded within the tethered endothelial cell membrane by membrane fusion for continuous NO releasing system. The catalytic tLB promoted endothelial cell attachment and inhibited smooth muscle cell growth, which can be applied for cardiovascular devices. In the further study, we fabricated a culture system for stem cell differentiation on the tLB derived from pre-differentiated cells, which can facilitate the stem cell differentiation without induction using growth factors. Taken together, our tLB systems pave the way for the versatile cell culture platform for biomedical applications. |
| 저자 |
이주로, Mahmoud A. Elnaggar, 정윤기
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| 소속 |
한국과학기술(연) |
| 키워드 |
Cell culture; cell membrane; tethered lipid bilayer
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| E-Mail |
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