화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2009년 봄 (04/15 ~ 04/17, 호텔인터불고(대구))
권호 13권 1호
발표분야 콜로이드계면화학
제목 Self-aggregation behavior of Poly(α,β-dimethylaminoethyl aspartamide) grafted withdidodecylamine in aqueous media
초록 Poly(α,β-dimethylaminoethyl aspartamide) grafted with didodecylamine was synthesized and confirmed by 1H-NMR. This polymer has amphiphilic property due to coexistence of hydrophilic polymer backbone and hydrophobic alkyl chain. It forms self-assembled structure with the direct dissolution method in aqueous solution and its behaviors can be controlled by changing degree of substitution (DS) which influences hydrophilic/hydrophobic ratio. Morphologies of aggregates were observed through the TEM image and (+) charge of the polymer backbone was proved by zeta potential. It is expected that this new polymer nano particle can be applied successfully as a drug carrier.
저자 심은송이, 이현진, 김종득
소속 KAIST
키워드 Self-aggregate; Poly(aspart amide); nano; drug carrier
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